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  標題:尿激酶在血液透析患者永久導管血栓形成中的應用
    

尿激酶在血液透析患者永久導管血栓形成中的應用
彭莉  禤偉振  歐陽梓華  蔡宗仰  容旭燕  蕭浤


【摘要】 

目的   觀察尿激酶在血透患者永久導管血栓形成後的溶栓效果。
方法   使用尿激酶(5000iu/ml)局部封管溶栓30~60min,觀察了導管溶栓前後動脈端血流量、靜脈端壓力狀態的改變以及溶栓治療的不良反應。
結果   20例患者、61例次、70個管腔內的尿激酶溶栓治療,動脈管腔溶栓成功47例(78.33%)。靜脈管腔溶栓成功9例(90%),總體溶栓成功率80%,未發現任何出血、過敏等副作用。
結論   應用尿激酶對永久導管血栓形成進行溶栓治療,效果好,安全性高,對恢復導管的功能和通暢性有很好的效果。

 

【關鍵詞】 尿激酶;血液透析;永久導管


Application of urokinase in the treatment of thrombosed permanent catheter of dialysis patient
HUN Wai Chan, AO Ieng Chi Wa, TSAI Tsung Yang, IONG Iok In, XIAO Hong
Departmemt of Internal Medicine, Kiang Wu Hospital. Macau

 

[Abstract] 

Objective    Retrospectively study the thrombolytic effect of urokinase in the treatment of thrombosed permanent catheter of dialysis patients.
Methods     Diluted urokinase (5000iu/ml) was instilled in thrombosed catheter for 30-60min, observed the change of arterial lumen blood flow and venous pressure in venous lumen during dialysis before and after the thrombolytic treatment. Side effects of the treatment were also recorded.
Results     Of 20 cases with 61 times and 70 lumens of thrombolytic treatments, 78.33% arterial lumen restored sufficient blood flow and 90% venous lumen pressure dropped to normal range to ensure an effective and fluent dialysis. The overall successful rate of thrombolytic treatment was 80%. No complication was recorded.
Conclusion Intracatheter thrombolysis treatment with urokinase is highly effective and safe in restoring the patency of occluded permanent catheter among hemodialysis patients.

 

[Key Words]  Urokinase; Hemodialysis; Permanent Catheter

 

 
   

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